DSIP
Delta sleep-inducing peptide
A nonapeptide first isolated in 1977 from the blood of sleeping rabbits. It was studied for decades in sleep and stress physiology, but its receptor and natural role are still unclear.
Structure
A nonapeptide with a single tryptophan at the N-terminus and an acidic, glycine-rich body. Select any residue to see what it is.
Evidence at a glance
Where the published research on DSIP comes from, by type of study.
Cell studies
Limited mechanistic work; no confirmed receptor.
Animal studies
Sleep architecture and stress hormone studies in rabbits and rats.
Human studies
Small studies from the 1980s with mixed results.
Research areas
What laboratories have studied DSIP for, and in which models. These are research questions, not proven uses.
Sleep studies
Rabbit EEG studiesRat models- Early reports of increased slow-wave sleep in rabbits; later studies were inconsistent.
Stress hormones
Rodent stress models- Studied for effects on corticotropin and stress responses.
Legal status
DSIP is not an approved medicine anywhere we cover. Suppliers may sell it for laboratory research only, and regulators judge that by the whole website, not the label.
United States Not approved
Not FDA-approved for any human use. May be sold for laboratory research only; FDA judges intended use from the whole website, not the label.
United Kingdom Not licensed
No MHRA licence. Sold with medicinal claims it counts as a medicine under the Human Medicines Regulations 2012.
European Union Not authorised
No EMA authorisation. Under Directive 2001/83/EC a substance can be a medicine by function, whatever its label says.
Sport Check S0
Not approved for human use, so it falls under WADA's S0 non-approved substances class. Check the current list.
Lab handling
General good practice for research materials. Follow the supplier's datasheet where it differs.
Storage
Keep the sealed material at −20 °C, dry and away from light. Let the vial reach room temperature before opening to stop condensation.
Solubility
Soluble in sterile water. Add solvent down the vial wall and swirl gently rather than shaking.
Aliquots
Split solutions into single-use aliquots, label with lot number and date, and freeze. Avoid repeated freeze-thaw cycles.
Work out your stock solution
Stock concentration, molarity and dilutions for DSIP, using MW 848.81 g/mol.
Before you buy for your lab
Tick each check as you confirm it with the supplier. Do not order until all six are done.
- Vendor claim: every batch is tested by accredited third-party labs at 99%+ purity. We have not yet verified a COA for this product.
- No dosing on product pages, and no FDA warning letter found as of 27 October 2026.
- Why Caution: its blog makes health and weight-loss claims that we do not endorse, it sells GLP-1 research compounds and injection-pen cartridges, and it does not verify researchers.
Questions researchers ask
What is DSIP?
A nonapeptide first isolated in 1977 from the blood of sleeping rabbits. It was studied for decades in sleep and stress physiology, but its receptor and natural role are still unclear.
What is the molecular weight of DSIP?
About 848.81 g/mol for the free peptide. Salt forms such as acetate weigh more, so use the figure on your batch certificate of analysis.
Is DSIP approved for human use?
No. Not FDA-approved for any human use. May be sold for laboratory research only; FDA judges intended use from the whole website, not the label.
How should DSIP be stored in the lab?
Keep the sealed material cold, dry and away from light, typically at −20 °C. Once in solution, split it into single-use aliquots and freeze to avoid repeated freeze-thaw cycles.
Does this page give doses?
No. We publish laboratory and educational information only, never doses, injection guidance or treatment advice.
