BPC-157
Body Protection Compound-157, a pentadecapeptide
A synthetic 15-amino-acid fragment of a protein found in gastric juice. It is one of the most studied peptides in rodent models of tendon, gut and wound repair. There are no published large controlled trials in people, and no regulator has approved it.
Structure
Fifteen residues, rich in proline, with two acidic aspartates near the C-terminus. Select any residue to see what it is.
Evidence at a glance
Where the published research on BPC-157 comes from, by type of study.
Cell studies
Fibroblast, endothelial and tendon cell cultures, looking at migration, growth factor signalling and blood vessel formation.
Animal studies
Mostly rats and mice: tendon and ligament injury, gut lesions, muscle, bone and nerve models.
Human studies
No large randomised controlled trials have been published. Safety and effect in people are unknown.
Research areas
What laboratories have studied BPC-157 for, and in which models. These are research questions, not proven uses.
Tendon and ligament repair
Rat Achilles transectionTendon fibroblast culture- Faster histological healing of transected tendons in rats.
- Increased growth hormone receptor expression in cultured tendon fibroblasts.
- Better outgrowth and survival of tendon cells in vitro.
Gastrointestinal protection
Rodent gastric lesion modelsColitis models- Stable in gastric juice, unusual for a peptide, which first drew interest.
- Reduced lesions in rodent models of ulcers and inflammatory bowel damage.
- Studied for fistula healing in animal models.
Wound healing and blood vessels
Endothelial cell assaysRodent skin wounds- Effects on VEGFR2 and nitric oxide pathways in endothelial cells.
- Faster closure of skin wounds and burns in animal models.
Muscle and bone
Rat muscle crush injurySegmental bone defect- Functional recovery after muscle injury in rats.
- Bone defect healing in rabbit and rat models.
Legal status
BPC-157 is not an approved medicine anywhere we cover. Suppliers may sell it for laboratory research only, and regulators judge that by the whole website, not the label.
United States Not approved
Not FDA-approved. Removed from the Category 2 bulk list on 15 April 2026 after its nomination was withdrawn; an advisory committee reviewed it in July 2026.
United Kingdom Not licensed
No MHRA licence. Sold with medicinal claims it counts as a medicine under the Human Medicines Regulations 2012.
European Union Not authorised
No EMA authorisation. Under Directive 2001/83/EC a substance can be a medicine by function, whatever its label says.
Sport Prohibited
Named by WADA as a non-approved substance, banned in and out of competition.
Lab handling
General good practice for research materials. Follow the supplier's datasheet where it differs.
Storage
Keep the sealed material at −20 °C, dry and away from light. Let the vial reach room temperature before opening to stop condensation.
Solubility
Generally soluble in sterile water or buffer. Add solvent down the vial wall and swirl gently rather than shaking.
Aliquots
Split solutions into single-use aliquots, label with lot number and date, and freeze. Avoid repeated freeze-thaw cycles.
Work out your stock solution
Stock concentration, molarity and dilutions for BPC-157, using MW 1419.53 g/mol.
Before you buy for your lab
Tick each check as you confirm it with the supplier. Do not order until all six are done.
- Vendor claim: every batch is tested by accredited third-party labs at 99%+ purity. We have not yet verified a COA for this product.
- No dosing on product pages, and no FDA warning letter found as of 27 October 2026.
- Why Caution: its blog makes health and weight-loss claims that we do not endorse, it sells GLP-1 research compounds and injection-pen cartridges, and it does not verify researchers.
Questions researchers ask
What is BPC-157?
A synthetic 15-amino-acid fragment of a protein found in gastric juice. It is one of the most studied peptides in rodent models of tendon, gut and wound repair. There are no published large controlled trials in people, and no regulator has approved it.
What is the molecular weight of BPC-157?
About 1419.53 g/mol for the free peptide. Salt forms such as acetate weigh more, so use the figure on your batch certificate of analysis.
Is BPC-157 approved for human use?
No. Not FDA-approved. Removed from the Category 2 bulk list on 15 April 2026 after its nomination was withdrawn; an advisory committee reviewed it in July 2026.
How should BPC-157 be stored in the lab?
Keep the sealed material cold, dry and away from light, typically at −20 °C. Once in solution, split it into single-use aliquots and freeze to avoid repeated freeze-thaw cycles.
Does this page give doses?
No. We publish laboratory and educational information only, never doses, injection guidance or treatment advice.
